Antibacterial Activity of Pregnenolone Derivatives

Abstract

Four new synthesized steroids, 3β-alloxy-5-pregnene-20-one 4, 3β-alloxy-5-pregene-17-oxime 5, 3β-stearoate-5-pregnene-20-one 6, 3β-stearoate-5pregnene-17-oxime 7, have been synthesized starting from 3β-hydroxy-5pregnene-20-one 3. The structures of theses steroids were confirmed by analytical and spectroscopic evidence. All of compounds were examined for antibacterial activity in vitro using the disc diffusion method.

Keywords: steroids; antibacterial activity; Disc diffusion method; pregnenolone

Corresponding author: E-mail: kcpatcha@kmitl.ac.th

How to Cite

Citation Format

Prabpayak, W. ., Charoenying*, P. ., Laosinwattana, C. ., & Aroonrerk, N. . (2018). Antibacterial Activity of Pregnenolone Derivatives. CURRENT APPLIED SCIENCE AND TECHNOLOGY, 466-470.

References

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Author Information

Wanawan Prabpayak

Department of Chemistry, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand.

Patchanee Charoenying*

Department of Chemistry, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand.

Chamroon Laosinwattana

Department of Horticulture, Faculty of Agricultural Technology, King Mongkut’s Institute of Technology Ladkrabang, Bangkok, Thailand.

Nuntana Aroonrerk

Department of Stomatology, Faculty of Dentistry, Srinakharinwirot University, Bangkok, Thailand.

About this Article

Journal

Vol. 6 No. 2b (2006)

Type of Manuscript

Original Research Article

Keywords

steroids; antibacterial activity; Disc diffusion method; pregnenolone

Published

30 March 2018

Antibacterial Activity of Pregnenolone Derivatives

Abstract

How to Cite

References

Author Information

Wanawan Prabpayak

Patchanee Charoenying*

Chamroon Laosinwattana

Nuntana Aroonrerk

About this Article

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